Application
Western blot analysis of anti-CCRK Pab in mouse kidney tissue lysate (35ug/lane). CCRK(arrow) was detected using the purified Pab (1:60 dilution).| Product Name | CCRK Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CCRK, CDCH |
|---|---|
| Alternative Names | CDK20 CCRK CDCH Cyclin-dependent kinase 20 CDK-activating kinase p42 Cell cycle-related kinase Cell division protein kinase 20 Cyclin-dependent protein kinase H Cyclin-kinase-activating kinase p42 |
| Molecular Weight(MW) | 38695 Da |
| Function | Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' |
| Tissue Specificity | This CCRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23~53 amino acids from the N-terminal region of human CCRK. |
| Cellular Localization | Nucleus. Cytoplasm (By similarity). Cell projection, cilium (By similarity) |
| Entrez Gene | 23552 |
|---|
Application
Western blot analysis of anti-CCRK Pab in mouse kidney tissue lysate (35ug/lane). CCRK(arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
