Application
CCRL2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CCRL2 antibody detected the CCRL2 protein (arrow).| Product Name | CCRL2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CCR11, CCR6, CKRX, CRAM, HCR |
|---|---|
| Alternative Names | CCRL2 CCR11 CCR6 CKRX CRAM HCR C-C chemokine receptor-like 2 Chemokine receptor CCR11 Chemokine receptor X Putative MCP-1 chemokine receptor |
| Molecular Weight(MW) | 39513 Da |
| Function | Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses |
| Tissue Specificity | Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow. Strong expression also in lung and heart. Expressed in almost all hematopoietic cells including monocytes, macrophages, PMNs, T- cells (both CD4+ and CD8+), monocyte-derived iDCs, NK cells, and CD34+ progenitor cells. B-cells expressed isoform 1 but not isoform 2. Up-regulated on synovial neutrophils of rheumatoid arthritis patients |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 9034 |
|---|---|
| Nucleotide Accession | NP_003956.2 |
Application
CCRL2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CCRL2 antibody detected the CCRL2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
