Application
A.Western blot analysis on (A) PBMC, (B) human tonsil and (C) SW480 cell lysates using anti-CD14 RabMAb (Cat. #AJ1151a), dilution 1:2000.Application
B.Immunohistochemical analysis of paraffin-embedded human placenta using anti-CD14 RabMAb (Cat. #AJ1151a).Application
C.Immunohistochemical analysis of paraffin-embedded human tonsil using anti-CD14 RabMAb (Cat. #AJ1151a).| Product Name | CD14 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3653 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CD14 Monocyte differentiation antigen CD14 membrane-bound form Myeloid cell-specific leucine-rich glycoprotein |
|---|---|
| Molecular Weight(MW) | 40076 Da |
| Function | In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules |
| Tissue Specificity | Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Entrez Gene | 929 |
|---|
Application
A.Western blot analysis on (A) PBMC, (B) human tonsil and (C) SW480 cell lysates using anti-CD14 RabMAb (Cat. #AJ1151a), dilution 1:2000.
Application
B.Immunohistochemical analysis of paraffin-embedded human placenta using anti-CD14 RabMAb (Cat. #AJ1151a).
Application
C.Immunohistochemical analysis of paraffin-embedded human tonsil using anti-CD14 RabMAb (Cat. #AJ1151a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
