Application
CD274 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD274 antibody detected the CD274 protein (arrow).| Product Name | CD274 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1; Programmed cell death 1 ligand 1; B7 homolog 1; CD_antigen=CD274; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | B7H1 PDCD1L1 PDCD1LG1 PDL1 |
|---|---|
| Alternative Names | CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 Programmed cell death 1 ligand 1 B7 homolog 1 CD_antigen=CD274 Flags: Precursor |
| Molecular Weight(MW) | 33275 Da |
| Function | Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production |
| Tissue Specificity | Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 29126 |
|---|---|
| Nucleotide Accession | NP_054862.1 |
Application
CD274 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD274 antibody detected the CD274 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
