Application
CD55 Antibody (Cat. #AM2092a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CD55 antibody detected the CD55 protein (arrow).| Product Name | CD55 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD55; CR; DAF; Complement decay-accelerating factor; CD_antigen=CD55; Flags: Precursor |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 561CT4.2.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~8000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CR DAF |
|---|---|
| Alternative Names | CD55 CR DAF Complement decay-accelerating factor CD_antigen=CD55 Flags: Precursor |
| Molecular Weight(MW) | 41400 Da |
| Function | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade |
| Tissue Specificity | Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 1604 |
|---|---|
| Nucleotide Accession | NP_000565.1 |
Application
CD55 Antibody (Cat. #AM2092a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CD55 antibody detected the CD55 protein (arrow).| Application Notes | WB:1:500~8000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
