Application
CDC14A Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CDC14A antibody detected the CDC14A protein (arrow).| Product Name | CDC14A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CDC14A Dual specificity protein phosphatase CDC14A CDC14 cell division cycle 14 homolog A |
|---|---|
| Molecular Weight(MW) | 66574 Da |
| Function | Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC- FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis |
| Tissue Specificity | This CDC14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CDC14A. |
| Cellular Localization | Nucleus. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle |
| Entrez Gene | 8556 |
|---|---|
| Nucleotide Accession | NP_003663.2 NP_201569.1 |
Application
CDC14A Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CDC14A antibody detected the CDC14A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
