Application
Western blot analysis of CDC16 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). CDC16 (arrow) was detected using the purified Pab.| Product Name | CDC16 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDC16; ANAPC6; Cell division cycle protein 16 homolog; Anaphase-promoting complex subunit 6; CDC16 homolog; Cyclosome subunit 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ANAPC6 |
|---|---|
| Alternative Names | CDC16 ANAPC6 Cell division cycle protein 16 homolog Anaphase-promoting complex subunit 6 CDC16 homolog Cyclosome subunit 6 |
| Molecular Weight(MW) | 71656 Da |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains |
| Tissue Specificity | This CDC16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDC16. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle |
| Entrez Gene | 8881 |
|---|
Application
Western blot analysis of CDC16 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). CDC16 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
