Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity
Tissue Specificity
This CDC25C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381~411 amino acids from the C-terminal region of human CDC25C.
Western blot analysis of anti-CDC25C Antibody (C-term) in K562 cell line lysates (35ug/lane).CDC25C(arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.