Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity
Tissue Specificity
A synthetic peptide corresponding to residues in C-terminus of human Cdc25C was used as immunogen. The antibody does not cross-react with other MPI phosphatase family members.