Application
CDCP1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDCP1 antibody detected the CDCP1 protein (arrow).| Product Name | CDCP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDCP1; TRASK; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; Transmembrane and associated with src kinases; CD_antigen=CD318; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TRASK |
|---|---|
| Alternative Names | CDCP1 TRASK CUB domain-containing protein 1 Membrane glycoprotein gp140 Subtractive immunization M plus HEp3-associated 135 kDa protein Transmembrane and associated with src kinases CD_antigen=CD318 Flags: Precursor |
| Molecular Weight(MW) | 92932 Da |
| Function | May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis |
| Tissue Specificity | Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass membrane protein (Potential). Note=Shedding may also lead to a soluble peptide |
| Entrez Gene | 64866 |
|---|---|
| Nucleotide Accession | NP_835488.1 NP_073753.3 |
Application
CDCP1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDCP1 antibody detected the CDCP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
