Application
Western blot analysis of CDKN2A (arrow) using rabbit polyclonal CDKN2A Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CDKN2A gene.Application
CDKN2A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CDKN2A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CDKN2A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDKN2A; CDKN2; MTS1; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; Multiple tumor suppressor 1; p16-INK4a |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CDKN2 MTS1 |
|---|---|
| Alternative Names | CDKN2A CDKN2 MTS1 Cyclin-dependent kinase inhibitor 2A isoforms 1/2/3 Cyclin-dependent kinase 4 inhibitor A Multiple tumor suppressor 1 p16-INK4a |
| Molecular Weight(MW) | 16533 Da |
| Function | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein |
| Tissue Specificity | Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 1029 |
|---|---|
| Nucleotide Accession | NP_000068.1 NP_478104.2 |
Application
Western blot analysis of CDKN2A (arrow) using rabbit polyclonal CDKN2A Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CDKN2A gene.
Application
CDKN2A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CDKN2A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
