Application
Western blot analysis of CEACAM3 (arrow) using rabbit polyclonal CEACAM3 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CEACAM3 gene.Application
CEACAM3 Antibody (C-term) (AP13855b)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CEACAM3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CEACAM3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD66D, CGM1 |
|---|---|
| Alternative Names | CEACAM3 CD66D CGM1 Carcinoembryonic antigen-related cell adhesion molecule 3 Carcinoembryonic antigen CGM1 CD_antigen=CD66d Flags: Precursor |
| Molecular Weight(MW) | 27091 Da |
| Function | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis |
| Tissue Specificity | CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 1084 |
|---|---|
| Nucleotide Accession | NP_001806.2 |
Application
Western blot analysis of CEACAM3 (arrow) using rabbit polyclonal CEACAM3 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CEACAM3 gene.
Application
CEACAM3 Antibody (C-term) (AP13855b)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CEACAM3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
