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CED6 Antibody (C-term)

Catalog Number:OM229560
OM229560
Discount Price
OM229560-100ul
1~2 Week
100ul
OM229560-50ul
50ul
OM229560-20ul
20ul
1~2 Week
Product Profile
Product Name CED6 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CED6, GULP
Alternative Names GULP1
CED6
GULP
PTB domain-containing engulfment adapter protein 1
Cell death protein 6 homolog
PTB domain adapter protein CED-6
Protein GULP
Molecular Weight(MW) 34490 Da
Function May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6
Tissue Specificity Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary
Cellular Localization Cytoplasm. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes
Database Links
Entrez Gene 51454
Application

Application

Western blot analysis of CED6 Antibody (C-term) in CEM cell line lysates (35ug/lane). CED6 (arrow) was detected using the purified Pab.

Application

CED6 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CED6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

CED6 Antibody (C-term) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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