Application
Western blot analysis of CENPI Antibody (Center) in CEM cell line lysates (35ug/lane). CENPI (arrow) was detected using the purified Pab.| Product Name | CENPI Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CENPI; FSHPRH1; ICEN19; LRPR1; Centromere protein I; FSH primary response protein 1; Follicle-stimulating hormone primary response protein; Interphase centromere complex protein 19; Leucine-rich primary response protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FSHPRH1 ICEN19 LRPR1 |
|---|---|
| Alternative Names | CENPI FSHPRH1 ICEN19 LRPR1 Centromere protein I FSH primary response protein 1 Follicle-stimulating hormone primary response protein Interphase centromere complex protein 19 Leucine-rich primary response protein 1 |
| Molecular Weight(MW) | 86720 Da |
| Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone |
| Tissue Specificity | This CENPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Central region of human CENPI. |
| Cellular Localization | Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex |
| Entrez Gene | 2491 |
|---|
Application
Western blot analysis of CENPI Antibody (Center) in CEM cell line lysates (35ug/lane). CENPI (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
