Application
CENPC1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CENPC1 antibody detected the CENPC1 protein (arrow).| Product Name | CENPC1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CENPC1; CENPC; ICEN7; Centromere protein C 1; Centromere autoantigen C; Interphase centromere complex protein 7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CENPC ICEN7 |
|---|---|
| Alternative Names | CENPC1 CENPC ICEN7 Centromere protein C 1 Centromere autoantigen C Interphase centromere complex protein 7 |
| Molecular Weight(MW) | 106834 Da |
| Function | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions |
| Tissue Specificity | This CENPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-475 amino acids from the Central region of human CENPC1. |
| Cellular Localization | Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres |
| Entrez Gene | 1060 |
|---|---|
| Nucleotide Accession | NP_001803.2 |
Application
CENPC1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CENPC1 antibody detected the CENPC1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
