Application
CENPO Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CENPO antibody detected the CENPO protein (arrow).| Product Name | CENPO Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CENPO; ICEN36; MCM21R; Centromere protein O; Interphase centromere complex protein 36 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ICEN36 MCM21R |
|---|---|
| Alternative Names | CENPO ICEN36 MCM21R Centromere protein O Interphase centromere complex protein 36 |
| Molecular Weight(MW) | 33786 Da |
| Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex |
| Tissue Specificity | This CENPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-69 amino acids from the N-terminal region of human CENPO. |
| Cellular Localization | Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex |
| Entrez Gene | 79172 |
|---|---|
| Nucleotide Accession | NP_077298.1 |
Application
CENPO Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CENPO antibody detected the CENPO protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
