CENPV; PRR6; Centromere protein V; Nuclear protein p30; Proline-rich protein 6
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PRR6
Alternative Names
CENPV PRR6 Centromere protein V Nuclear protein p30 Proline-rich protein 6
Molecular Weight(MW)
29946 Da
Function
Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis
Tissue Specificity
This CENPV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Central region of human CENPV.
Cellular Localization
Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Enriched at the nuclear periphery and around the nucleolus. In mitotic cells, localizes to kinetochores from prometaphase to metaphase. At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis
Western blot analysis of CENPV Antibody (Center) in HL-60 cell line lysates (35ug/lane). CENPV (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.