Application
CEP63 Antibody (Center) western blot analysis in WiDr,293 cell line lysates (35ug/lane).This demonstrates the CEP63 antibody detected the CEP63 protein (arrow).Application
CEP63 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CEP63 Antibody (Center)) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CEP63 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CEP63 Centrosomal protein of 63 kDa |
|---|---|
| Molecular Weight(MW) | 81344 Da |
| Function | Required for normal spindle assembly. Maintains centrosome numbers through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (By similarity) |
| Tissue Specificity | This CEP63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527~556 amino acids from the Central region of human CEP63. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Note=Colocalizes with CEP152 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles |
| Entrez Gene | 80254 |
|---|
Application
CEP63 Antibody (Center) western blot analysis in WiDr,293 cell line lysates (35ug/lane).This demonstrates the CEP63 antibody detected the CEP63 protein (arrow).
Application
CEP63 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CEP63 Antibody (Center)) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
