Application
Western blot analysis of CEP55 Antibody (N-term) in MDA-MB231, T47D cell line lysates (35ug/lane). CEP55 (arrow) was detected using the purified Pab.| Product Name | CEP55 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C10orf3, URCC6 |
|---|---|
| Alternative Names | CEP55 C10orf3 URCC6 Centrosomal protein of 55 kDa Up-regulated in colon cancer 6 |
| Molecular Weight(MW) | 54178 Da |
| Function | Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis |
| Tissue Specificity | Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, centrosome. Cleavage furrow Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis |
| Entrez Gene | 55165 |
|---|
Application
Western blot analysis of CEP55 Antibody (N-term) in MDA-MB231, T47D cell line lysates (35ug/lane). CEP55 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
