Application
Western blot analysis of CES3 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). CES3 (arrow) was detected using the purified Pab.| Product Name | CES3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CES3; Carboxylesterase 3; Liver carboxylesterase 31 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CES3 Carboxylesterase 3 Liver carboxylesterase 31 homolog |
|---|---|
| Molecular Weight(MW) | 62282 Da |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics |
| Tissue Specificity | Expressed in liver, colon and small intestine. |
| Cellular Localization | Endoplasmic reticulum lumen (By similarity). |
| Entrez Gene | 23491 |
|---|
Application
Western blot analysis of CES3 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). CES3 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
