Application
Western blot analysis of CFL2 (arrow) using rabbit polyclonal CFL2 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CFL2 gene.Application
CFL2 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the CFL2 antibody detected the CFL2 protein (arrow).Application
CFL2 Antibody (N-term) (AP14117a)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CFL2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CFL2; Cofilin-2; Cofilin, muscle isoform |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CFL2 Cofilin-2 Cofilin muscle isoform |
|---|---|
| Molecular Weight(MW) | 18737 Da |
| Function | Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity) |
| Tissue Specificity | Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues |
| Cellular Localization | Nucleus matrix (By similarity). Cytoplasm, cytoskeleton (By similarity) |
| Entrez Gene | 1073 |
|---|---|
| Nucleotide Accession | NP_619579.1 NP_068733.1 |
Application
Western blot analysis of CFL2 (arrow) using rabbit polyclonal CFL2 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CFL2 gene.
Application
CFL2 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the CFL2 antibody detected the CFL2 protein (arrow).
Application
CFL2 Antibody (N-term) (AP14117a)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
