Application
Western blot analysis of CHIA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). CHIA (arrow) was detected using the purified Pab.Application
CHIA Antibody (N-term) FC analysis of ZR-75-1 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CHIA Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHIA; Acidic mammalian chitinase; Lung-specific protein TSA1902 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CHIA Acidic mammalian chitinase Lung-specific protein TSA1902 |
|---|---|
| Molecular Weight(MW) | 52271 Da |
| Function | Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13 Stimulates chemokine production by pulmonary epithelial cells Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding |
| Tissue Specificity | Detected in lung epithelial cells from asthma patients (at protein level). Highly expressed in stomach. Detected at lower levels in lung |
| Cellular Localization | Isoform 1: Secreted. Note=Secretion depends on EGFR activity Isoform 3: Cytoplasm. |
| Entrez Gene | 27159 |
|---|
Application
Western blot analysis of CHIA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). CHIA (arrow) was detected using the purified Pab.
Application
CHIA Antibody (N-term) FC analysis of ZR-75-1 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
