Application
CHORDC1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CHORDC1 antibody detected the CHORDC1 protein (arrow).| Product Name | CHORDC1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHORDC1; CHP1; Cysteine and histidine-rich domain-containing protein 1; CHORD domain-containing protein 1; Protein morgana |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CHP1 |
|---|---|
| Alternative Names | CHORDC1 CHP1 Cysteine and histidine-rich domain-containing protein 1 CHORD domain-containing protein 1 Protein morgana |
| Molecular Weight(MW) | 37490 Da |
| Function | Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis |
| Tissue Specificity | Underexpressed in many breast and lung cancers |
| Entrez Gene | 26973 |
|---|---|
| Nucleotide Accession | NP_036256.2 |
Application
CHORDC1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CHORDC1 antibody detected the CHORDC1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
