Application
CHST14 Antibody (Center) western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the CHST14 antibody detected CHST14 protein (arrow).| Product Name | CHST14 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHST14; D4ST1; Carbohydrate sulfotransferase 14; Dermatan 4-sulfotransferase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | D4ST1 |
|---|---|
| Alternative Names | CHST14 D4ST1 Carbohydrate sulfotransferase 14 Dermatan 4-sulfotransferase 1 |
| Molecular Weight(MW) | 42997 Da |
| Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development |
| Tissue Specificity | Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 113189 |
|---|---|
| Nucleotide Accession | NP_569735.1 |
Application
CHST14 Antibody (Center) western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the CHST14 antibody detected CHST14 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
