Application
CHST8 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CHST8 antibody detected the CHST8 protein (arrow).| Product Name | CHST8 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHST8; Carbohydrate sulfotransferase 8; GalNAc-4-O-sulfotransferase 1; N-acetylgalactosamine-4-O-sulfotransferase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CHST8 Carbohydrate sulfotransferase 8 GalNAc-4-O-sulfotransferase 1 N-acetylgalactosamine-4-O-sulfotransferase 1 |
|---|---|
| Molecular Weight(MW) | 48834 Da |
| Function | Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin |
| Tissue Specificity | Predominantly expressed in pituitary gland. In brain, it is expressed in pituitary gland, cerebellum, medulla oblongata, pons, thalamus and spinal cord. Expressed in the epidermis. Expressed at lower level in lung, spleen, adrenal gland, placenta, prostate, testis, mammary gland and trachea |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 64377 |
|---|---|
| Nucleotide Accession | NP_071912.2 NP_001121367.1 NP_001121368.1 |
Application
CHST8 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CHST8 antibody detected the CHST8 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
