Application
Western blot analysis of CK051 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). CK051 (arrow) was detected using the purified Pab.| Product Name | CK051 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANAPC15; C11orf51; Anaphase-promoting complex subunit 15 |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | C11orf51 |
|---|---|
| Alternative Names | ANAPC15 C11orf51 Anaphase-promoting complex subunit 15 |
| Molecular Weight(MW) | 14281 Da |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20 |
| Tissue Specificity | This CK051 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45~74 amino acids from the Central region of human CK051. |
| Entrez Gene | 25906 |
|---|
Application
Western blot analysis of CK051 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). CK051 (arrow) was detected using the purified Pab.| Application Notes | WB:1:500~1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
