Application
CLDN1 Antibody (Loop1) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CLDN1 antibody detected the CLDN1 protein (arrow).Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with hCLDN1-Loop1 , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | Claudin 1 (CLDN1) Antibody (Loop1) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLD1 SEMP1 |
|---|---|
| Alternative Names | CLDN1 CLD1 SEMP1 Claudin-1 Senescence-associated epithelial membrane protein |
| Molecular Weight(MW) | 22744 Da |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity). Acts as a co- receptor for HCV entry into hepatic cells |
| Tissue Specificity | Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis |
| Cellular Localization | Cell junction, tight junction (By similarity). Cell membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 9076 |
|---|
Application
CLDN1 Antibody (Loop1) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CLDN1 antibody detected the CLDN1 protein (arrow).
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with hCLDN1-Loop1 , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
