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Claudin 1 (CLDN1) Antibody (Loop2)

Catalog Number:OM229883
OM229883
Discount Price
OM229883-100ul
1~2 Week
100ul
OM229883-50ul
50ul
OM229883-20ul
20ul
1~2 Week
Product Profile
Product Name Claudin 1 (CLDN1) Antibody (Loop2)
Antibody Type Primary Antibodies
Antigen Alias CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:50~100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CLD1
SEMP1
Alternative Names CLDN1
CLD1
SEMP1
Claudin-1
Senescence-associated epithelial membrane protein
Molecular Weight(MW) 22744 Da
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity). Acts as a co- receptor for HCV entry into hepatic cells
Tissue Specificity Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis
Cellular Localization Cell junction, tight junction (By similarity). Cell membrane; Multi-pass membrane protein (By similarity)
Database Links
Entrez Gene 9076
Application

Application

Western blot analysis of anti-hCLDN1-Loop2 Pab in mouse kidney tissue lysates (35ug/lane). CLDN1(arrow) was detected using the purified Pab (1:60 dilution).

Application

Western blot analysis of CLDN1 (arrow) using rabbit polyclonal CLDN1 Antibody (Loop2) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLDN1 gene.
Application Notes WB:1:50~100
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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