CLEC12A Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CLEC12A antibody detected the CLEC12A protein (arrow).
CLEC12A CLL1 DCAL2 MICL C-type lectin domain family 12 member A C-type lectin-like molecule 1 Dendritic cell-associated lectin 2 Myeloid inhibitory C-type lectin-like receptor
Molecular Weight(MW)
30762 Da
Function
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases
Tissue Specificity
Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages
Cellular Localization
Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization
CLEC12A Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CLEC12A antibody detected the CLEC12A protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.