CLEC2D Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLEC2D antibody detected the CLEC2D protein (arrow).
CLEC2D; CLAX; LLT1; OCIL; C-type lectin domain family 2 member D; Lectin-like NK cell receptor; Lectin-like transcript 1; Osteoclast inhibitory lectin
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CLAX LLT1 OCIL
Alternative Names
CLEC2D CLAX LLT1 OCIL C-type lectin domain family 2 member D Lectin-like NK cell receptor Lectin-like transcript 1 Osteoclast inhibitory lectin
Molecular Weight(MW)
21849 Da
Function
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans
Tissue Specificity
Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells
Cellular Localization
Cell membrane; Single-pass type II membrane protein. Cell surface Isoform 4: Endoplasmic reticulum.
CLEC2D Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLEC2D antibody detected the CLEC2D protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.