Application
CLEC6A Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CLEC6A antibody detected the CLEC6A protein (arrow).| Product Name | CLEC6A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLEC6A; CLECSF10; DECTIN2; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLECSF10 DECTIN2 |
|---|---|
| Alternative Names | CLEC6A CLECSF10 DECTIN2 C-type lectin domain family 6 member A C-type lectin superfamily member 10 Dendritic cell-associated C-type lectin 2 |
| Molecular Weight(MW) | 23998 Da |
| Function | Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity) |
| Tissue Specificity | Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells. Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially expressed in plasmacytoids rather than myeloids |
| Cellular Localization | Membrane; Single-pass type II membrane protein (Probable) |
| Entrez Gene | 93978 |
|---|---|
| Nucleotide Accession | NP_001007034.1 |
Application
CLEC6A Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CLEC6A antibody detected the CLEC6A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
