Application
Western blot analysis of anti-CLIC5 Antibody in K562 cell line lysates (35ug/lane). CLIC5(arrow) was detected using the purified Pab (1:60dilution).Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with CLIC5 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | CLIC5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLIC5; Chloride intracellular channel protein 5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CLIC5 Chloride intracellular channel protein 5 |
|---|---|
| Molecular Weight(MW) | 46503 Da |
| Function | Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion Required for normal formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture |
| Tissue Specificity | Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level) |
| Cellular Localization | Isoform 1: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Membrane; Single-pass membrane protein Note=Associates with the cortical actin cytoskeleton. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity) |
| Entrez Gene | 53405 |
|---|
Application
Western blot analysis of anti-CLIC5 Antibody in K562 cell line lysates (35ug/lane). CLIC5(arrow) was detected using the purified Pab (1:60dilution).
Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with CLIC5 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
