Application
Western blot analysis of anti-hCLK1-C84 Pab in Y79 cell line lysate. hCLK1-C84(arrow) was detected using the purified Pab.| Product Name | CLK1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLK |
|---|---|
| Alternative Names | CLK1 CLK Dual specificity protein kinase CLK1 CDC-like kinase 1 |
| Molecular Weight(MW) | 57291 Da |
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA |
| Tissue Specificity | Endothelial cells. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 1195 |
|---|
Application
Western blot analysis of anti-hCLK1-C84 Pab in Y79 cell line lysate. hCLK1-C84(arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
