Application
The anti-CLK3 Pab is used in Western blot to detect CLK3 in mouse skeletal muscle tissue lysate.Application
Western blot analysis of CLK3 (arrow) using rabbit polyclonal CLK3 Antibody (Y26) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLK3 gene.| Product Name | CLK3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLK3; Dual specificity protein kinase CLK3; CDC-like kinase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CLK3 Dual specificity protein kinase CLK3 CDC-like kinase 3 |
|---|---|
| Molecular Weight(MW) | 73515 Da |
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells |
| Tissue Specificity | Endothelial cells. |
| Cellular Localization | Isoform 1: Nucleus. Cytoplasm (By similarity). Cytoplasmic vesicle, secretory vesicle, acrosome (By similarity) |
| Entrez Gene | 1198 |
|---|
Application
The anti-CLK3 Pab is used in Western blot to detect CLK3 in mouse skeletal muscle tissue lysate.
Application
Western blot analysis of CLK3 (arrow) using rabbit polyclonal CLK3 Antibody (Y26) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLK3 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
