Application
CMBL Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CMBL antibody detected the CMBL protein (arrow).Application
CMBL Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CMBL antibody detected the CMBL protein (arrow).Application
CMBL Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CMBL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CMBL Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CMBL Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CMBL; Carboxymethylenebutenolidase homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CMBL Carboxymethylenebutenolidase homolog |
|---|---|
| Molecular Weight(MW) | 28048 Da |
| Function | Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin |
| Tissue Specificity | Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level) |
| Cellular Localization | Cytoplasm, cytosol. |
| Entrez Gene | 134147 |
|---|---|
| Nucleotide Accession | NP_620164.1 |
Application
CMBL Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CMBL antibody detected the CMBL protein (arrow).
Application
CMBL Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CMBL antibody detected the CMBL protein (arrow).
Application
CMBL Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CMBL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CMBL Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
