Application
CMIP Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CMIP antibody detected the CMIP protein (arrow).| Product Name | CMIP Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CMIP; KIAA1694; TCMIP; C-Maf-inducing protein; Truncated c-Maf-inducing protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1694 TCMIP |
|---|---|
| Alternative Names | CMIP KIAA1694 TCMIP C-Maf-inducing protein Truncated c-Maf-inducing protein |
| Molecular Weight(MW) | 86331 Da |
| Function | Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor |
| Tissue Specificity | Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver |
| Cellular Localization | Nucleus. Cytoplasm. Note=Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS). Detected in nuclear and cytoplasmic compartments during MCNS relapse. Expressed in cytoplasm only during MCNS remission and absent in normal patients |
| Entrez Gene | 80790 |
|---|---|
| Nucleotide Accession | NP_085132.1 |
Application
CMIP Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CMIP antibody detected the CMIP protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
