Application
Western blot analysis of CMPK2 Antibody (Center) in Hela cell line lysates (35ug/lane).CMPK2 (arrow) was detected using the purified Pab.Application
CMPK2 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CMPK2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CMPK2 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CMPK2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CMPK2; UMP-CMP kinase 2, mitochondrial |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CMPK2 UMP-CMP kinase 2 mitochondrial |
|---|---|
| Molecular Weight(MW) | 49448 Da |
| Function | May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs |
| Tissue Specificity | Among all investigated tumors, leukemia cells show the most abundant expression |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 129607 |
|---|
Application
Western blot analysis of CMPK2 Antibody (Center) in Hela cell line lysates (35ug/lane).CMPK2 (arrow) was detected using the purified Pab.
Application
CMPK2 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CMPK2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CMPK2 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
