Application
CNGA4 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CNGA4 antibody detected the CNGA4 protein (arrow).Application
CNGA4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CNGA4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CNGA4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CNGA4; Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CNGA4 Cyclic nucleotide-gated cation channel alpha-4 Cyclic nucleotide-gated channel alpha-4 |
|---|---|
| Molecular Weight(MW) | 65999 Da |
| Function | Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs) CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity) |
| Tissue Specificity | This CNGA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from the N-terminal region of human CNGA4. |
| Cellular Localization | Membrane; Multi-pass membrane protein (Potential) |
| Entrez Gene | 1262 |
|---|---|
| Nucleotide Accession | NP_001032406.1 |
Application
CNGA4 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CNGA4 antibody detected the CNGA4 protein (arrow).
Application
CNGA4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CNGA4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
