Application
CNO6L Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CNO6L Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CNO6L Antibody (C-term) western blot analysis in Sk-Br-3 cell line tissue lysates (35ug/lane).This demonstrates the CNO6L antibody detected the CNO6L protein (arrow).| Product Name | CNO6L Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CNOT6L; CCR4B; CCR4-NOT transcription complex subunit 6-like; Carbon catabolite repressor protein 4 homolog B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CCR4B |
|---|---|
| Alternative Names | CNOT6L CCR4B CCR4-NOT transcription complex subunit 6-like Carbon catabolite repressor protein 4 homolog B |
| Molecular Weight(MW) | 63001 Da |
| Function | Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation- dependent degradation of CDKN1B mRNA |
| Tissue Specificity | Highly expressed in placenta, skeletal muscle, pancreas, testis and leukocytes. Weakly expressed in heart, spleen and thymus |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 246175 |
|---|
Application
CNO6L Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CNO6L Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CNO6L Antibody (C-term) western blot analysis in Sk-Br-3 cell line tissue lysates (35ug/lane).This demonstrates the CNO6L antibody detected the CNO6L protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
