Application
CNOT6 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CNOT6 antibody detected the CNOT6 protein (arrow).| Product Name | CNOT6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CNOT6; CCR4; KIAA1194; CCR4-NOT transcription complex subunit 6; CCR4 carbon catabolite repression 4-like; Carbon catabolite repressor protein 4 homolog; Cytoplasmic deadenylase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CCR4 KIAA1194 |
|---|---|
| Alternative Names | CNOT6 CCR4 KIAA1194 CCR4-NOT transcription complex subunit 6 CCR4 carbon catabolite repression 4-like Carbon catabolite repressor protein 4 homolog Cytoplasmic deadenylase |
| Molecular Weight(MW) | 63307 Da |
| Function | Poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Has 3'-5' RNase activity. The CCR4-NOT complex functions as general transcription regulation complex (By similarity). In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any |
| Tissue Specificity | This CNOT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 415-442 amino acids selected from the C-terminal region of human CNOT6. |
| Cellular Localization | Cytoplasm (Probable). Nucleus (Probable). |
| Entrez Gene | 57472 |
|---|---|
| Nucleotide Accession | NP_056270.2 |
Application
CNOT6 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CNOT6 antibody detected the CNOT6 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
