The protein encoded by this gene belongs to the
G-protein-coupled receptor family . It is a receptor for the CC
chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group
of small polypeptide, structurally related molecules that regulate
cell trafficking of various types of leukocytes. The chemokines
also play fundamental roles in the development, homeostasis, and
function of the immune system, and they have effects on cells of
the central nervous system as well as on endothelial cells involved
in angiogenesis or angiostasis.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.