Application
Western blot analysis of CNTN6 Antibody (Center) in HL-60 cell line lysates (35ug/lane). CNTN6 (arrow) was detected using the purified Pab.| Product Name | CNTN6 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CNTN6; Contactin-6; Neural recognition molecule NB-3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CNTN6 Contactin-6 Neural recognition molecule NB-3 |
|---|---|
| Molecular Weight(MW) | 113956 Da |
| Function | Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity) |
| Tissue Specificity | Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor (By similarity) |
| Entrez Gene | 27255 |
|---|
Application
Western blot analysis of CNTN6 Antibody (Center) in HL-60 cell line lysates (35ug/lane). CNTN6 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
