Application
Western blot analysis of COL25A1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). COL25A1 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human Brain with COL25A1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | COL25A1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COL25A1; Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; CLAC-P; Collagen-like Alzheimer amyloid plaque component |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | COL25A1 Collagen alpha-1(XXV) chain Alzheimer disease amyloid-associated protein CLAC-P Collagen-like Alzheimer amyloid plaque component |
|---|---|
| Molecular Weight(MW) | 64771 Da |
| Function | Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin |
| Tissue Specificity | Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease |
| Cellular Localization | Membrane; Single-pass type II membrane protein (Potential). Note=After proteolytic cleavage, CLAC is secreted |
| Entrez Gene | 84570 |
|---|
Application
Western blot analysis of COL25A1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). COL25A1 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human Brain with COL25A1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
