Application
COPG2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the COPG2 antibody detected the COPG2 protein (arrow).Application
COPG2 Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COPG2 Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | COPG2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COPG2; Coatomer subunit gamma-2; Gamma-2-coat protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | COPG2 Coatomer subunit gamma-2 Gamma-2-coat protein |
|---|---|
| Molecular Weight(MW) | 97622 Da |
| Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) |
| Tissue Specificity | This COPG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-824 amino acids from the C-terminal region of human COPG2. |
| Cellular Localization | Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity) |
| Entrez Gene | 26958 |
|---|---|
| Nucleotide Accession | NP_036265.3 |
Application
COPG2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the COPG2 antibody detected the COPG2 protein (arrow).
Application
COPG2 Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COPG2 Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
