Application
COPZ1 Antibody (N-term) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).Application
COPZ1 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).| Product Name | COPZ1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COPZ1; COPZ; Coatomer subunit zeta-1; Zeta-1-coat protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | COPZ |
|---|---|
| Alternative Names | COPZ1 COPZ Coatomer subunit zeta-1 Zeta-1-coat protein |
| Molecular Weight(MW) | 20198 Da |
| Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) |
| Tissue Specificity | This COPZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human COPZ1. |
| Cellular Localization | Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity) |
| Entrez Gene | 22818 |
|---|---|
| Nucleotide Accession | NP_057141.1 |
Application
COPZ1 Antibody (N-term) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).
Application
COPZ1 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
