Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases
Tissue Specificity
A synthetic peptide corresponding to residues near the C-terminus of human cortactin was used as an immunogen.
Cellular Localization
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. Note=Associated with membrane ruffles and lamellipodia