Application
Western blot analysis of CPE antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). CPE (arrow) was detected using the purified Pab.Application
Western blot analysis of CPE antibody (C-term) in Hela cell line lysates (35ug/lane). CPE (arrow) was detected using the purified Pab.| Product Name | CPE Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPE; Carboxypeptidase E; Carboxypeptidase H; Enkephalin convertase; Prohormone-processing carboxypeptidase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CPE Carboxypeptidase E Carboxypeptidase H Enkephalin convertase Prohormone-processing carboxypeptidase |
|---|---|
| Molecular Weight(MW) | 53151 Da |
| Function | Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing Processes proinsulin |
| Tissue Specificity | Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas |
| Cellular Localization | Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein (By similarity) Secreted (By similarity). Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions (By similarity) |
| Entrez Gene | 1363 |
|---|
Application
Western blot analysis of CPE antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). CPE (arrow) was detected using the purified Pab.
Application
Western blot analysis of CPE antibody (C-term) in Hela cell line lysates (35ug/lane). CPE (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
