Application
CPSF3L Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CPSF3L antibody detected the CPSF3L protein (arrow).Application
CPSF3L Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CPSF3L Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of CPSF3L Antibody (N-term)(Cat#AP11162a) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | CPSF3L Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPSF3L; INTS11; RC68; Integrator complex subunit 11; Cleavage and polyadenylation-specific factor 3-like protein; Protein related to CPSF subunits of 68 kDa |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | INTS11 RC68 |
|---|---|
| Alternative Names | CPSF3L INTS11 RC68 Integrator complex subunit 11 Cleavage and polyadenylation-specific factor 3-like protein Protein related to CPSF subunits of 68 kDa |
| Molecular Weight(MW) | 67663 Da |
| Function | Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage |
| Tissue Specificity | This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human CPSF3L. |
| Cellular Localization | Nucleus. Cytoplasm. |
| Entrez Gene | 54973 |
|---|---|
| Nucleotide Accession | NP_060341.2 |
Application
CPSF3L Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CPSF3L antibody detected the CPSF3L protein (arrow).
Application
CPSF3L Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CPSF3L Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of CPSF3L Antibody (N-term)(Cat#AP11162a) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
