Application
Western blot analysis of CPSF5 in mouse bladder tissue lysates (35ug/lane). CPSF5 (arrow) was detected using the purified Pab.| Product Name | CPSF5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NUDT21; CFIM25; CPSF25; CPSF5; Cleavage and polyadenylation specificity factor subunit 5; Cleavage and polyadenylation specificity factor 25 kDa subunit; Nucleoside diphosphate-linked moiety X motif 21; Pre-mRNA cleavage factor Im 25 kDa subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CFIM25 CPSF25 CPSF5 |
|---|---|
| Alternative Names | NUDT21 CFIM25 CPSF25 CPSF5 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor 25 kDa subunit Nucleoside diphosphate-linked moiety X motif 21 Pre-mRNA cleavage factor Im 25 kDa subunit |
| Molecular Weight(MW) | 26227 Da |
| Function | Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export |
| Tissue Specificity | This CPSF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155~185 amino acids from the center region of human CPSF5. |
| Cellular Localization | Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles |
| Entrez Gene | 11051 |
|---|
Application
Western blot analysis of CPSF5 in mouse bladder tissue lysates (35ug/lane). CPSF5 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
