CPSF6 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CPSF6 antibody detected the CPSF6 protein (arrow).
CPSF6; CFIM68; Cleavage and polyadenylation specificity factor subunit 6; Cleavage and polyadenylation specificity factor 68 kDa subunit; Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII-4/7
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CFIM68
Alternative Names
CPSF6 CFIM68 Cleavage and polyadenylation specificity factor subunit 6 Cleavage and polyadenylation specificity factor 68 kDa subunit Pre-mRNA cleavage factor Im 68 kDa subunit Protein HPBRII-4/7
Molecular Weight(MW)
59210 Da
Function
Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping
Tissue Specificity
This CPSF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human CPSF6.
Cellular Localization
Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles
CPSF6 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CPSF6 antibody detected the CPSF6 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.